11/28/2022 0 Comments Degenesis pdf torrent![]() After the consumption of fish or seafood, methylmercury is absorbed in the intestinal tract and can pass the blood-brain barrier and also enters the placenta. įor humans, fish and seafood consumption is the most important exposure pathway. Overall, the highest methylmercury levels are found in predatory fish and big, old marine mammals. Methylmercury accumulates in the marine food chain. Fish and marine mammals ingest methylmercury with their food and fish additionally absorb it through the gills. It predominantly arises from the methylation of inorganic mercury by the action of microorganisms in aquatic systems. Methylmercury is regarded as one of the most toxic mercury compounds. The remaining disease burden was a result of severe mental retardation with equal proportions of premature death and morbidity. Of the total disease burden, 98% were attributed to mild mental retardation, which only leads to morbidity. ![]() A large majority of the DALYs was attributed to morbidity as compared to mortality. The methylmercury-induced burden of disease for the German birth cohort 2014 was an average of 14,186 DALY (95% CI 12,915–15,440 DALY). Thus, one DALY corresponds to the loss of one year of life in good health. DALYs combine mortality and morbidity in one measure and quantify the gap between an ideal situation, where the entire population experiences the standard life expectancy without disease and disability, and the actual situation. Subsequently, we calculated the disease burden with the disability-adjusted life years (DALY)-method. ![]() ![]() To quantify this disease burden, we used Monte Carlo simulation to estimate the incidence of mild and severe mental retardation in children born to mothers who consume fish based on empirical data. Prenatal methylmercury exposure is associated with IQ loss. Humans are mainly exposed to methylmercury when they eat fish or seafood. This study aimed to estimate the disease burden of methylmercury for children born in Germany in the year 2014. ![]()
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